ABSTRACT
<p><b>OBJECTIVE</b>To explore the relationship between immunochemical level of salivary and caries in children aged 4-6 years old.</p><p><b>METHODS</b>Two groups were assorted as patients with caries and without caries. Every group included 45 people. Measurements of salivary secretory immunoglobulin A (SIgA)were performed by using radio-immunoassay and single agar diffusion assay. The levels of lysozyme (LZ), alkaline phosphatase (ALP) and lactic dehydrogenase (LDH) were studied with colorimetry and turbidimentry.</p><p><b>RESULTS</b>The levels of LDH, SigA, ALP, LZ had significant difference between the two groups (P < 0.05). The level of LDH between patients and peoples without caries had little difference (P > 0.05).</p><p><b>CONCLUSION</b>The incidence of caries is associated with age, and it may have association with immunochemical levels of salivary.</p>